The Anti-dsDNA test determines the total amount of antibody to double-stranded Anti-dsDNA (deoxyribonucleic acid) that may be contaminating the blood. Sometimes, our immune system fails to distinguish between ‘Self’ and ‘Non-self’ cellular components. This leads to the production of an autoantibody called Anti-dsDNA. Mistakenly, it targets and attacks the body’s, own genetic material. This causes tissue damage, inflammation, and other signs and symptoms associated with an immune disorder.
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The Anti-dsDNA test at a glance.
Some other famous names for the test are:
Why is the Anti-dsDNA test needed?
The test help in diagnosing and monitoring systemic lupus erythematosus (SLE)
When is the Anti-dsDNA test needed?
The Anti-dsDNA test is needed when a person has symptoms associated with SLE. The test is also required when the person has a positive ANA result.
What is the Sample required for Anti-dsDNA?
The Anti-dsDNA test requires a blood sample which is drawn from a vein in the arm.
What are the test preparations needed for Anti-dsDNA?
Just relax, you need not to prepare for the Anti-dsDNA test.
What is being tested in an Anti-dsDNA test?
Our body has several antinuclear antibodies (ANA), one of them is Anti dsDNA antibodies. It is a set of antibodies which are pointed against substances in the cell nucleus. While their numbers may be less or they may be present with a number of disorders. The anti-dsDNA is mainly related to SLE or Lupus (systemic lupus erythematosus). The organs which are affected because of SLE are kidneys, joints, blood vessels, skin, heart, lungs, and the brain. The common symptoms can be seen as rashes, fatigue, kidney dysfunction, and joint pain. SLE is usually seen in women aged 15-40. It is more common in non-Caucasians. Until now no direct cause is known, there might exist some genetic predisposition. High level of anti dsDNA indicates damage to the kidneys and ongoing inflammation. ANA test is used to detect autoimmune disorder.
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