- Chromosomal Microarray (CMA-315K) (1)
- Chromosomal Microarray (CMA-315K)
- Maternal Cell Contamination (MCC) (1)
- Maternal Cell Contamination (MCC)
- QF-PCR- 13, 18, 21, X & Y (1)
- QF-PCR- 13, 18, 21, X & Y
The QF-PCR (Basic) + CMA (315K) + MCC test is a comprehensive genetic testing panel used in prenatal diagnosis. It includes three important components:
- Chromosomal Microarray (CMA-315K): This test is a high-resolution genomic analysis that detects copy number variations (CNVs) across the entire genome. It is used to identify gains or losses of genetic material, which can be associated with various genetic disorders and developmental abnormalities.
- Maternal Cell Contamination (MCC): This test is performed to determine if there is contamination of the prenatal sample with the mother’s cells. It is crucial to ensure accurate results, as the presence of maternal cells can interfere with the interpretation of fetal genetic information.
- QF-PCR- 13, 18, 21, X & Y: Quantitative Fluorescent Polymerase Chain Reaction (QF-PCR) is a rapid and sensitive method used to detect specific chromosomal abnormalities, particularly aneuploidies of chromosomes 13, 18, 21, X, and Y. These chromosomes are commonly associated with conditions like Down syndrome (trisomy 21), Edwards syndrome (trisomy 18), and Patau syndrome (trisomy 13).
The QF-PCR (Basic) + CMA (315K) + MCC test is typically ordered during prenatal screening or diagnosis when there is a concern about fetal chromosomal abnormalities or genetic disorders. It provides comprehensive information about the fetal genome and can aid in making informed decisions regarding pregnancy management and counseling.