Beta Thalassemia Screening Test

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- Home Sample Collection
- Genuine Bar coded Reports
5 Tests | Pay @ Home | Rs 460 |
Free Home Collection | 10 – 12 Hours Fasting Required | You can consume water during fasting.
- THALASSEMIA [5]
- HEMOGLOBIN A2
- HEMOGLOBIN C
- HEMOGLOBIN D
- HEMOGLOBIN F
- HEMOGLOBIN S
Thalassemia is a genetic blood disorder that affects the production of hemoglobin, a protein that carries oxygen in red blood cells. There are different types of thalassemia, depending on which genes are affected and to what extent.
Hemoglobin A2, Hemoglobin C, Hemoglobin D, Hemoglobin F, and Hemoglobin S are different types of hemoglobin variants that can be present in individuals with thalassemia. Each of these variants has a different effect on the severity and presentation of thalassemia.
Hemoglobin A2 (HbA2) is a normal variant of hemoglobin that makes up a small percentage of the total hemoglobin in healthy individuals. In individuals with beta thalassemia, the level of HbA2 may be increased. The measurement of HbA2 levels is used as a diagnostic tool for beta thalassemia trait.
Hemoglobin C (HbC) is a variant of hemoglobin that can cause mild hemolytic anemia. In individuals with hemoglobin C disease, the HbC variant is present in both copies of the beta-globin gene. Hemoglobin C trait occurs when only one copy of the beta-globin gene is affected.
Hemoglobin D (HbD) is a variant of hemoglobin that can cause moderate hemolytic anemia. In individuals with hemoglobin D disease, the HbD variant is present in both copies of the beta-globin gene. Hemoglobin D trait occurs when only one copy of the beta-globin gene is affected.
Hemoglobin F (HbF) is the fetal variant of hemoglobin that is normally replaced by adult hemoglobin after birth. In individuals with beta thalassemia, the level of HbF may be increased as a compensatory mechanism for the reduced or absent production of adult hemoglobin.
Hemoglobin S (HbS) is a variant of hemoglobin that causes sickle cell disease. In individuals with sickle cell disease, the HbS variant is present in both copies of the beta-globin gene. Hemoglobin S trait occurs when only one copy of the beta-globin gene is affected.
The importance of these hemoglobin variants in thalassemia lies in their diagnostic and prognostic value, as well as their influence on the severity and presentation of the disease. The identification and measurement of these hemoglobin variants can aid in the diagnosis and classification of different types of thalassemia and guide the management and treatment of affected individuals.
Is there any difference between thalassemia test and Beta thalassemia test?
Yes, there is a difference between Thalassemia test and Beta Thalassemia test.
Thalassemia is a group of inherited blood disorders that affect the production of hemoglobin, a protein that carries oxygen in red blood cells. There are two main types of thalassemia: alpha thalassemia and beta thalassemia, each caused by mutations in different genes.
A thalassemia test is a general term that refers to a group of blood tests that are used to detect the presence of thalassemia, but it does not specify which type of thalassemia is being tested.
On the other hand, a beta thalassemia test specifically tests for mutations in the beta-globin gene that cause beta thalassemia, which is the more common and severe type of thalassemia. Beta thalassemia test measures the amount of hemoglobin A2 and hemoglobin F, and detects mutations in the beta-globin gene that can lead to reduced or absent production of beta-globin chains.
In summary, while all beta thalassemia tests are a type of thalassemia test, not all thalassemia tests are beta thalassemia tests.